Sunday, October 28, 2012

Acyclovir Pharmacology and Indication



Acyclovir is acyclic purine nucleoside analogue active against herpes simplex virus, varicella zoster, Epstein-Barr virus and cytomegalovirus. In the cell, undergo phosphorylation acyclovir acyclovir triphosphate into an active form that inhibit the herpes simplex virus DNA polymerase and viral DNA replication, thereby preventing viral DNA synthesis without

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